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复方泽漆散对肿瘤组织转化生长因子—β_1表达的影响 被引量:20

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摘要 目的 :探讨复方泽漆散对小鼠Lewis肺癌的抑制作用及其对转化生长因子 - β1(TGF - β1)表达的影响。方法 :本研究是以移植性C57BL/ 6小鼠Lewis肺癌为动物模型 ,观察复方泽漆散对小鼠Lewis肺癌的抑制作用 ,通过免疫组织化学方法 ,观察复方泽漆散对肿瘤组织转化生长因子 - β1表达的影响。结果 :复方泽漆散能够抑制Lewis肺癌肿瘤细胞生长 ,稳定病灶 ,下调TGF - β1的表达。结论 :复方泽漆散对小鼠Lewis肺癌具有明显疗效 ,其作用机理与降低TGF - β1的表达有关。
出处 《中医药信息》 2004年第3期68-70,共3页 Information on Traditional Chinese Medicine
基金 黑龙江中医管理局资金课题 (2 0 0 2 0 )
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