摘要
目的 :评价药物涂层冠状动脉内支架的早期疗效。方法 :2 0 0 2年 9月～ 2 0 0 3年 4月 10 2例冠心病患者接受药物涂层冠状动脉内支架术治疗 (14 1枚 ,药物支架组 ) ,随机选择同期 10 2例接受普通、非药物涂层支架治疗 (15 8枚 ,裸支架组 ) ,比较两组支架置入情况及早期临床事件发生率。结果 :两组手术成功率相似 (10 0 %∶99.0 % ,P >0 .0 5 )。平均随访 (4 .9± 3.3)个月 ,随访率 87.2 % ,药物支架组心绞痛复发率显著低于裸支架组(7.8%∶2 3.5 % ,P <0 .0 1)。结论
Objective:To evaluate the short-term efficacy of coronary drug-eluting stent(DES) in patients with coronary artery disease(CAD). Method:From September 2002 to Apr 2003, 102 patients were treated with 141 coronary drug-eluting stents(DES group).The short-term follow-up outcomes of these patients were compared with another 102 well-matched cases who received 158 standard uncoated stents(control group) within the same time period. Result: Baseline clinical characteristics were similar between the two groups.Severity and type of the lesions of coronary arteries in the two groups were comparable. Stents deployed in the DES group were smaller, but the length of the stents in both groups were similar.Angiographic success rate (100% vs 99.0%, P> 0.05) and stenting procedure were comparable in the two groups.During mean 4.9 months of follow-up ,the rate of recurrent angina pectoris was significantly lower in the DES group than that in the control group( 23.5% ∶ 7.8%, P= 0.003). There were no major cardiac events in the two groups. Conclusion: As compared with standard uncoated coronary stent, DES provides better short-term clinical efficacy.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2004年第5期279-281,共3页
Journal of Clinical Cardiology
