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小分子玉米肽Leu-Asp-Tyr-Glu保护线粒体抗氧化损伤的研究 被引量:11

Protection of Small Molecule Corn Peptide Leu-Asp-Tyr-Glu from Mitochondria Against Oxidative Damage
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摘要 A small molecule peptide Leu-Asp-Tyr-Glu(LDYE) prepared from the enzymatic hydrolysate of zein was tested for its anti-oxidative activities. The effects of LDYE on the turgidity of mitochondria,the fluidity of membrane,the activity of cytochrome C oxidase and ATPase at subcellular level were investigated by using H\-2O\-2/Fe\+\{2+\} -induced mitochondria damage model system. It was found that the small peptide exhibited an obvious ability of removing free radicals and protecting the mitochondria from damage by oxidation. [WT5HZ] A small molecule peptide Leu-Asp-Tyr-Glu(LDYE) prepared from the enzymatic hydrolysate of zein was tested for its anti-oxidative activities. The effects of LDYE on the turgidity of mitochondria,the fluidity of membrane,the activity of cytochrome C oxidase and ATPase at subcellular level were investigated by using H\-2O\-2/Fe\+\{2+\} -induced mitochondria damage model system. It was found that the small peptide exhibited an obvious ability of removing free radicals and protecting the mitochondria from damage by oxidation. [WT5HZ]
出处 《高等学校化学学报》 SCIE EI CAS CSCD 北大核心 2004年第6期1073-1075,共3页 Chemical Journal of Chinese Universities
基金 国家"十五"科技攻关计划项目 (批准号 :2 0 0 1BA747C)资助
关键词 玉米肽 线粒体 抗氧化活性 Corn peptide Mitochondria Anti-oxidation activity
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