摘要
目的 :探讨血小板相关抗体在血小板减少症中的临床应用。方法 :选择健康者、血小板低于正常的体检者、血小板减少性紫癜(ITP)、再障 (AA)、肝脏疾患、系统性红斑狼疮 (SLE)患者等采用ELISA法定量测定血小板抗体PAIgG、PAIgM、PAIgA ,并分析ITP患者治疗前后血小板相关抗体的变化。结果 :血小板低于正常的体检者血小板抗体的阳性率 14 .9% ,ITP、AA、SLE等患者血小板相关抗体阳性率与正常组比较有显著差异 ,分别为 78.9%、3 1.2 %、62 .5 % ,肝病者血小板相关抗体与正常组无差异。ITP患者治疗前后三种血小板抗体均有非常显著性变化 (P <0 .0 1)。结论
Objective: To study the clinical appliance of platelet associated antibody in thrombocytopenic diseases.Method: The platelet associated Ig(PAIgG?PAIgM?PAIgA) of the healthy people and the patients with lower blood platelet?idiophathic thrombocytopenic purpura(ITP)?aplastic anemia(AA)?systemic lupus erythematosus(SLE) were measured by ELISA.Results: The positive rate of platelet antibody in the people with lower platelet is 14.9%;there are significant difference between the ITP?AA?SLE and the healthy group,and there are not difference between the liver diseases group and healthy group.Conclusion: Platelet antibody detection has important significance for diagnosis and treatment of autoimmune disease.
出处
《微循环学杂志》
2004年第2期52-53,共2页
Chinese Journal of Microcirculation
