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组胺与中枢神经系统疾病 被引量：8

Histamine and diseases of central nervous system
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摘要 组胺是炎症介质 ,也是中枢神经系统中的一种重要的神经递质或神经调质。近年来的研究发现 ,脑内组胺参与了多种中枢神经系统疾病 ,如阿尔茨海默病、癫痫、帕金森病以及脑缺血性疾病。深入研究组胺与中枢神经系统疾病的内在关系 ,研究和开发组胺类药物 ,将为中枢神经系统疾病的治疗开拓新的方向。
作者 陈忠 胡薇薇
机构地区 浙江大学医学院药理学教研室
出处 《浙江大学学报（医学版）》 CAS CSCD 2004年第3期185-188,共4页 Journal of Zhejiang University(Medical Sciences)
基金 国家自然科学基金资助项目( No 30 0 0 0 019 30 3716 38) 浙江省青年人才基金资助项目( R30 3779)
关键词 组胺 中枢神经系统疾病
分类号 R741 [医药卫生—神经病学与精神病学]
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参考文献32

  • 1SCHWARTZ J C,ARRANG J M,GARBARG M,et al.Histaminergic transmission in the mammalian brain [J].Physiol Rev,1991,71(1):1-51.
  • 2PANULA P,RINNE J,KUOKKANEN K,et al.Neuronal histamine deficit in Alzheimer's disease [J].Neurosci,1997,82(4):993-997.
  • 3NAKAMURA S,TAKEMURA M,OHNISHI K,et al.Loss of large neurons and occurrence of neurofibrillary tangles in the tuberomammillary nucleus of patients with Alzheimer's disease [J].Neurosci Lett,1993,151(2):196-199.
  • 4CHEN Z,KAMEI C.Facilitating effects of histamine on spatial memory deficit induced by scopolamine in rats [J].Acta Pharmacol Sin,2000,21(9):814-818.
  • 5HUANG Y W,CHEN Z,HU W W,et al.Facilitating effect of histamine on spatial memory deficits induced by dizocilpine as evaluated by 8-arm radial maze in SD rats [J].Acta Pharmacol Sin,2003,24(12):1 270-1 276.
  • 6HUANG Y W,HU W W,CHEN Z,et al.Effect of clobenpropit on spatial memory deficits induced by MK-801 as evaluated by radial maze in Sprague-Dawley rats [J].Behav Brain Res,2004,151(1-2):287-293.
  • 7CHEN Z,ZHAO Q E,SUGIMOTO Y,et al.Effects of histamine on MK-801-induced memory deficits in radial maze performance in rats [J].Brain Res,1999,839(1):186-189.
  • 8CHEN Z,SUGIMOTO Y,KAMEI C.Effects of intracerebroventricular injection of α-fluoromethylhistidine on radial maze performance in rats [J].Pharmacol Biochem Behav,1999,64(3):513-518.
  • 9BEKKERS J M.Enhancement by histamine of NMDA-mediated synaptic transmission in the hippocampus [J].Science,1993,261(5117):104-106.
  • 10DAIHai-bin CHENZhong HUANGYu-wen etal(戴海斌 陈忠 黄育文 ).Reversing effect of histamine on neuron death induced by N—methyl—D—asparate [J].Journal of Zhejiang University:Medical Sciences (浙江大学学报:医学版),2004,33(3):189-192.

二级参考文献9

  • 1HUANG Y W,HU W W,CHEN Z,et al.Effect of clobenpropit on spatial memory deficits induced by MK-801 as evaluated by radial maze in Sprague-Dawley rats [J].Behav Brain Res,2004,151(1-2):287-293.
  • 2XU A J,CHEN Z,YANAI K,et al.Effect of 3-[1-(phenylmethyl)-4-piperidinyl]-1- (2,3,4,5-tetrahydro-1H-1-benzazepin-8-yl)-1-propanone fumarate,a novel acetylcholinesterase inhibitor,on spatial cognitive impairment induced by chronic cerebral hypoperfusion in rats [J].Neurosci Lett,2002,331(1):33-36.
  • 3GENKOVA-PAPAZOVA M G,PETKOVA B,SHISH-KOVA N,et al.Effect of the calcium channel blockers nifedipine and diltiazem on pentylenetetrazole kindling-provoked amnesia in rats [J].Eur Neuropsychopharmacol,2001,11(2):91-96.
  • 4ZHANG L S,CHEN Z,HUANG Y W,et al.Effects of endogenous histamine on seizure development of pentylenetetrazole-induced kindling in rats [J].Pharmacology,2003(1),69:27-32.
  • 5ZHANG L S,CHEN Z,REN K M,et al.Effects of clobenpropit on penylenetetrazole-kindled seizures in rats [J].Eur J Pharmacol,2003,482(1-3):169-175.
  • 6XU A-jing,CHEN Zhong,Li Ren,et al (徐阿晶,陈忠,李韧,等).Effects of TAK-147,a novel acetylcholinesterase inhibitor,on spatial memory deficits as valuated by Morris Water maze of rats [J].Journal of Zhejiang University:Medical Sciences (浙江大学学报:医学版),2002,31(2):98-102.(in Chinese)
  • 7SERRA M,DAZZI L,PISU M G,et al.Reversal of a selective decrease in hippocampal acetylcholine release,but not of the persistence of kindling,after discontinuation of long-term pentylenetetrazol administration in rats [J].Brain Res,1997,751(1):175-179.
  • 8CHEN Z,KAMEI C.Facilitating effects of histamine on spatial memory deficit induced by scopolamine in rats [J].Acta Pharmacol Sin,2000,21(9):814-818.
  • 9TOYOTA H,ITO C,OHSAWA M,et al.Decreased central histamine in the amygdaloid kindling rats [J].Brain Res,1998,802(1-2):241-246.

共引文献18

同被引文献87

引证文献8

二级引证文献53

浙江大学学报（医学版）
2004年 第3期

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