摘要
目的 :探讨复方氨基酸注射液所致不良反应的一般规律及特点 ,指导临床合理用药。方法 :对医药期刊报道的 1 37例复方氨基酸的ADR进行统计分析。结果 :复方氨基酸所致ADR在高年龄组发生率较高 ,多在用药过程中半小时内发生。ADR累及机体多个器官系统 ,临床表现复杂多样 ,主要表现为变态反应 ,严重者可致过敏性休克甚至死亡。结论 :应加强复方氨基酸的应用监测 。
OBJECTIVE: To study the general pattern and characteristics of ADRs induced by compound amino acid injection(Co-AA)to guide rational drug use. METHODS: An analysis was conducted on 137 cases of ADRs induced by Co-AA reported in domestic medical journals.RESULTS: ADRs of Co-AA often occurred in aged group. The onset of ADRs was usually within 30min after injection. ADRs could involve in multiple organs and systems, and clinical manifestations were various, mainly were allergic reaction. Severe allergic reaction could result in anaphylactic shock and even death.CONCLUSION: the use of Co-AA should be under strict monitoring to reduce the occurrence of serious ADRs.
出处
《中国医院用药评价与分析》
2004年第2期114-117,共4页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
复方氨基酸注射液
不良反应
变态反应
合理用药
compound amino acid
adverse drug reaction(ADR)
analysis of the literature
