摘要
目的探讨用气相色谱法同时测定化妆品中苯甲醇、苯氧基乙醇、对羟基苯甲酸甲酯(PHBA鄄Me)、对羟基苯甲酸乙酯(PHBA鄄Et)、对羟基苯甲酸异丙酯(PHBA鄄iPr)、对羟基苯甲酸丙酯(PHBA鄄Pr)、对羟基苯甲酸异丁酯(PHBA鄄iBu)和对羟基苯甲酸丁酯(PHBA鄄Bu)等8种防腐剂。方法样品经甲醇提取后,用5%SE鄄30填充柱对上述8种防腐剂进行气相色谱分析。结果该方法对上述8种防腐剂的检出限分别是0.27、0.38、0.78、0.83、0.95、1.40、1.50和2.10ng;苯甲醇、苯氧基乙醇和PHBA鄄iPr的线性范围均为25～1000mg/L,PHBA鄄Me、PHBA鄄Et、PHBA鄄Pr、PHBA鄄iBu和PHBA鄄Bu的线性范围均为25～500mg/L;回收率92.6%～101.3%;相对标准偏差(RSD)为3.31%～6.44%(n=6)。结论该方法简便、快速、灵敏、重现性好,能很好地分离上述8种防腐剂,抗干扰能力强,适用于化妆品中防腐剂的检验。
Objective To develop a gas chromatographic (GC)method for simultaneously determination of benzyl alcohol,2-phenoxyethanol,methyl-p-hydroxy benzoate (PHBA-Me?雪,ethyl-p-hydroxybenzoate(PHBA-Et?雪,isooropyl-p-hydroxybenzoate(PHBA-iPr?雪,propyl-p-hydroxybenzoate (PHBA-Pr),isobuty-p-hydroxy benzoate(PHBA-iBu)and butyl-p-hydroxy benzoate(PHBA-Bu)in cosmetics. Methods The 8 kinds of preservatives could be separated completely using the packed column and their peaks were not interfered by the other components in cosmetics. Results The detection limits of were 0.27,0.38,0.78,0.83,0.95,1.40,1.50 and 2.1ng respectively. The linear ranges of benzyl alcohol,2-phenoxyethanol and PHBA-iPr were 25-1 000 mg/L and the linear ranges of PHBA-Me?PHBA-Et?PHBA-Pr?PHBA-iBu and PHBA-Bu were 25-500 mg/L. The recoveries were between 92.6%-101.3% and the relative standard deviations(RSD)were between 2.31%-6.44%(n=6?雪. Conclusion The method was simple,rapid,sensitive and accurate. It was suitable for the detecting of preservatives in cosmetics.
出处
《环境与健康杂志》
CAS
CSCD
北大核心
2004年第3期170-171,共2页
Journal of Environment and Health
关键词
色谱法
气相
防腐剂
化妆品
Chromatography gas
Preservative
Cosmetic
