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幽门螺杆菌耐药机制研究近况

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出处 《临床内科杂志》 CAS 北大核心 2004年第5期359-360,共2页 Journal of Clinical Internal Medicine
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  • 1Alarcon T, Dominge D, Prieto N, Lopez-Brca M, et al. PCR using 3'mismatched primers to detect A2142C mutation in 23s rRNA conferring resistance to clarithromycin in Helicobacter pylori clinical isolates. J Clin Micrebio1,2000,38(2) :923-925.
  • 2Van-Doom LJ,Glupczynski Y. Accurate Prediction of Macrolide Resistance in Helicobacter pylori by a PCR Line Probe Assay for Detection of Mutations in the 23S rRNA Gene: Muhicenter Validation Study. Antimicreb Agents Chemotber,2001,45 (5): 1500-1504.
  • 3郑小丽,胡伏莲,王蔚虹,成虹.北京地区幽门螺杆菌对克拉霉素的耐药情况及其耐药机制[J].中华医学杂志,2001,81(23):1413-1415. 被引量:23
  • 4Fontana C, Favaro M, Minelli S, et al. New site of modification of 23srRNA associated with clarithromycin resistance of Helicobacter pylori clinical isolates. Antimicrob Agents Chemother, 2002,46 ( 12 ): 3765-3769.
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  • 6Debets-Ossenkopp YJ, Raymond GJP, David J vW, et al. Insertion of mini-IS605 and deletion of adjacant sequences in the nitroreductase (rdxA) gene cause metronidazole resistance in Helicobacter pylofi NCTC11637. Antimicrob Agents Chemother, 1999, 43 ( 11 ): 2657-2662.
  • 7Latham SR, Owen RI. Differentiation of metrenidazole-sonsitive and -resistant clinical isolates of Helicobacter pylori by Immunoblotting with Antisera to the rdxA protein. J Clin Microbiol, 2001,39 ( 9 ): 3052-3055.
  • 8Kwon DH ,El -Zaatari FA, Kato M, et al. Analysis of rdxA and involvement of additional genes enceding NAD (P) H flavin oxidoreductase (FrxA) and fermedoxin-like protein (FdxB) in metronidazole resistance of Helieobacter pylori. Antimicreb Agents Chemother, 2000,44 ( 8 ):2133-2142.
  • 9Jeong JY, Mukhopadhyay AK, Dailidiene D, et al. Sequential inactivation of rdxA ( HP0954 ) and frxA ( HP0642 ) nitroreductese genes causes moderate and high-level metronidazole resistance in Helicobacter pylori.J Bacteriol,2000,182(18) :5082-5090.
  • 10Armelle M,Claudio B,Cantet F. Chamcterization of the genes rdxA and frxA involved in metronidazole resistance in Helicobacter pylori. Research in Microbiology. 2003,154 (2) :137-144.

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