摘要
抗菌肽又称抗微生物肽(antimicrobial peptide)或肽抗生素(peptide antibiotics),在动植物体内分布广泛,是天然免疫防御系统的一部分。抗菌肽不仅有广谱抗细菌能力,而且对真菌、病毒及癌细胞也有作用。对抗菌肽作用机理的研究是近来的热点之一,本文综述了此方面近来的进展,并对微生物针对抗菌肽的耐药性进行了讨论。
Antimicrobial peptides or peptide antibiotics, a part of innate immune system, are widely spread in both plants and animals. They have a wide antibacterial spectrum, and some even have effects on fungi, virus and cancer cells. Recent study of their mechanism and resistance is rather intensive, which will be reviewed in this article.
出处
《细胞生物学杂志》
CSCD
北大核心
2004年第2期125-128,共4页
Chinese Journal of Cell Biology
基金
国家自然科学基金资助项目(No.39870552)~~
