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肾移植术后重症肺部感染两种治疗方案的比较 被引量:11

Comparison of two protocols for the treatment of severe pneumonia after renal transplantation
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摘要 目的 :提高肾移植术后重症肺部感染的治疗水平。方法 :6 3例肾移植术后重症肺部感染患者依抗细菌方案的不同分为A、B两组 ,A组抗生素由高档到低档 ,B组与之相反 ,其余治疗不变。结果 :A组治愈率、ARDS救治成功率为 87.9%、76 .9% ,B组为 5 6 .7%、12 .5 % ;治疗中发展为ARDS、混合感染及多器官感染的例数A组为 2例、4例、4例 ,B组为 7例、10例、13例 ;A组住院天数 ( 31± 7)d ,住院费用 ( 7.3± 2 .2 )千元 ,B组为 ( 5 3± 9)d和 ( 13.9± 5 .7)千元。两组相差显著。结论 :肾移植术后重症肺部感染的治疗A方案优于B方案。 Objective:To evaluate the efficacy of two protocols in renal transplant recipients with severe pneumonia . MethodsSixty three patients underwent severe pneumonia after renal transplantation were divided into two groups:group A(33 cases) were treated with antibacterial from high grade to low grade,group B(30 cases) were treated with antibacterial from low grade to high grade , all other treatments were the same.Results: The cure rate of pneumonia and emergency treatment of ARDS in group A were 87.9%, 76.9% and 56.7%,12.5% in group B. The cases exacerbated with ARDS, mixed infection and multi-organ infection were 2,4,4 in group A and 7,10,13 in group B. The time and the cost of hospitalization were (31±7) days and (7.3±2.7)thousands yuan in group A, while in group B ,they were (53±9) days and (13.9±5.7) thousands yuan.The difference was significant ( P <0.01).Conclusion:The protocol with antibacterial from high grade to low grade is better than that from low grade to high grade in renal transplant recipients with severe pneumonia.
出处 《西北国防医学杂志》 CAS 2004年第2期122-123,共2页 Medical Journal of National Defending Forces in Northwest China
关键词 肾移植 重症肺部感染 治疗 Renal transplantation Severe pneumonia Treatment
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  • 1[1]Tveit DJ,Hypolite IO, Poropatich RK, et al. Hospitalizations for bacterial pneumonia after renal transplantation in the United States[J].Nephrol,2002 , 15(3):255-262.
  • 2[2]Dharnidharka VR,Harmon WE. Management of pediatric postrenal transplantation infections [J].Semin Nephrol, 2001, 21(5):521-531.
  • 3[3]EBPG Expert Group on Renal Transplantation. European best practice guidelines for renal transplantation. Section IV: Long-term management of the transplant recipient. IV.7.1 Late infections. Pneumocystis carinii pneumonia[J]. Nephrol Dial Transplant,2002, 17 Suppl 4: 36-39.
  • 4[4]UchidaK,NakayamaH, Yoshida,K, et al. Opportunistic pneumonia after kidney transplantation [J].Nihon Kokyuki Gakkai Zasshi,2001,39(3): 166-171.
  • 5[5]SileriP,PursellKJ, CoadyNT,et al. A standardized protocol for the treatment of severe pneumonia in kidney transplant recipients [J].Clin Transplant,2002,16(6): 450-454.

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