摘要
肾移植后感染是术后最主要的并发症,常见于呼吸系统,具有病原种类繁多、病情发展快,死亡率高,病原体检测困难等特点,也是肾移植患者的主要死因。从抗生素选择、免疫调节剂的使用、糖皮质激素的应用和营养支持及对症治疗等方面优化治疗方案,并以血药浓度监测、关注潜在的药物相互作用及不良反应和减少药物对移植肾的损害作为监护要点来反馈治疗方案的效果,保证患者用药安全、有效。
After renal transplantation, infection is the major complications, common in the respiratory system, with a wide range of pathogens, quickly development and high mortality, which is also the fatal cause of death for kidney transplant patients. Optimize antibiotics, immunomodulatory agents, glucocorticoids, nutritional support while blood concentration monitoring, concerning about po- tential drug interactions and adverse reactions and reduction the drugs damage to the transplanted kidney could be positive for treat- ment. Clinical pharmacologist should be a effectual component in working group to ensure the safe and effective in patients with medi- cation.
出处
《科技视界》
2012年第20期314-315,共2页
Science & Technology Vision
关键词
肾移植
肺部感染
药学监护
Renal transplantation
Pulmonary infection
Pharmaceutical care
