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高海拔地区严重烧伤延迟复苏合并多脏器功能障碍临床研究 被引量:5

Delayed resuscitation in severely burned patients with multiple organ dysfunction syndrome at high altitude
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摘要 目的 :探讨高海拔地区严重烧伤延迟复苏与即时复苏合并多脏器功能障碍综合征 (MODS)发病特征、机率和结局的关系。方法 :参照国内外MODS两个诊断评分标准 ,对本院近 10年符合重度烧伤标准病例 (年龄 >9岁 ) ,分为即时复苏组 (A组 ,n =30 )和延迟复苏组 (B组 ,n =35 ) ,对比观察两组发生SIRS ,MODS ,MOF的机率。结果 :全组 6 5例 ,均满足SIRS 4项标准中的 2项。A组满足 3项和 4项分别为 11例、1例 ;B组分别为 18例、12例 ,两组差异显著 (P <0 .0 1) ;A组MODS ,MOF的发生率和死亡率分别为 33.33%、13.3%、14 .2 9% ,B组分别为 78.0 6 %、34.2 8%、36 .77%。结论 :①高海拔地区严重烧伤SIRS反应 ,具有较高的敏感性和较低的特异性的特点 ;②高海拔地区严重烧伤合并MODS的结局重于平原地区 ;③延迟复苏组的SIRS、MODS、MOF发生率明显高于即时复苏组。 Objective:To investigate the pathogenic character, morbidity and outcome between the delayed resuscitation and the immediate resuscitation in the burned patients with multiple organ dysfunction syndrome (MODS) in the high altitude area.Methods:Referring to the two diagnostic standards in domestic and abroad,65 (aged over 9) severely burned patients with MODS were divided into two groups ,the delayed resuscitation group (group A, n =30) and the immediate resuscitation group (group B, n =35) .We summed up and compared the morbidity of SIRS,MODS and MOF of the two groups. ResultsOf 4 items to diagnose SIRS, all patients accorded with over 2 items. The patients according with 3 items were 11 cases in group A and 18 cases in group B, and according with 4 items were one case in group A and 12 cases in group B( P <0.01). The Morbidity of MODS, MOF and the mortality was 33.33%,13.3%,14.29% respectively in group A and 78.06%,34.28%,36.77% in group B.Conclusion:①The higher sensitivity and lower specialization of SIRS in severely burned patients appear in the high altitude area. ②Outcome of severely burned patients with MODS in the high altitude area is worse than that in plain area. ③The disease incidences of SIRS, MODS and MOF in group A are significantly higher than those in group B .
出处 《西北国防医学杂志》 CAS 2004年第2期88-90,共3页 Medical Journal of National Defending Forces in Northwest China
基金 全军"十五"医药卫生重点科研基金资助项目 (0 1-L0 0 3 )
关键词 延迟复苏 烧伤 全身炎性反应综合征 多脏器功能障碍综合征 高海拔地区 Delayed resuscitation Burn Systemic inflammatory response syndrome Multiple organ dysfunction syndrome High altitude area
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