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一对一系统家庭干预降低精神分裂症复发的随机对照研究 被引量:21

Effect of one-to-one system family intervention on the reduction of schizophrenia relapse:A randomized controlled study
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摘要 目的:探讨对精神分裂症患者及家属进行一对一系统家庭干预的可行性和长期效果。方法:将200例精神分裂症患者及家属按入院顺序分层随机法,分为研究组和对照组,待患者病情缓解出院后随访3年。前半年进行10次系统精神医学知识指导,研究组一对一干预,对照组集体干预,于入、出院时和出院3年末评定两组功能缺陷量表(DAS)、阳性和阴性症状量表(PANSS)、家属满意度及复发情况。结果:出院3年末:研究组和对照组脱落为14例(14.0%)和37例(37.0%);复发18例(20.9%)和24例(38.1%);满意、不满意54例(62.8%)、12例(13.9%)和28例(44.5%)、21例(33.3%),经χ2检验,都有显著性或极显著性差异(χ2=4.9,P<0.05;χ2=8.4,P<0.01)。DAS总分5.4±4.4和11.0±4.1,经t检验有显著性差异(t=2.4,P<0.05)。首次住院者的脱落率和复发率显著低于第2次住院者。结论:一对一系统家庭干预能提高疗效,有效降低复发率,提高患者的社会功能。 AIM:To explore the feasibility and long term effect of one to one system family intervention to patients with schizophrenia and their relatives. METHODS:200 patients with schizophrenia and relatives were divided into study group and control group randomly according to the subsequence of hospitalization,they were followed up for 3 years after discharge.They accepted ten cathedras about systematical psyche medical knowledge in the first half year,the study group was intervened one to one while the control group collectively.Both groups were evaluated with the DAS,PANSS, satisfactory degree of relatives and relapse condition when entered and left the hospital and at the end of the 3rd years, respectively. RESULTS:At the end of the 3rd year after discharge: the loss in the study group and the control group was 14 cases(14.0%) and 37 cases(37.0%), relapse was 18 cases(20.9%) and 24 cases(38.1%), satisfied was 54 cases(62.8%) and 28 cases(44.5%) ,unsatisfied 12 cases (13.9%) and 21 cases(33.3%). The differences were all significant with χ2 test(χ2=4.9,P< 0.05;χ2=8.4,P< 0.01 ).The total score of DAS were(5.4±4.4)and(11.0±4.1),which were significantly different with t test(t=2.4,P< 0.05 ).The loss rate and relapse rate in the patients who were in hospital for the first time were significantly lower than those for the second time.
出处 《中国临床康复》 CSCD 2003年第30期4114-4115,共2页 Chinese Journal of Clinical Rehabilitation
关键词 一对一系统家庭干预 精神分裂症 复发 社会功能 综合治疗 One to one family intervention can not only enhance the effect and reduce the relapse rates of schizophrenia ,but also improve their social functions.
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