摘要
本文用放射免疫法测定58例胃癌、43例胃起性疾病、24例食管癌患者及158例健康成人血清与胃液中的CEA及Ft。结果表明,胃癌患者血清CEA水平高于正常对照组,P<0.01,但与胃良性疾病及食管癌纽问的差异不明显;胃癌患者血清Ft水平低于各对照组,P<0.01;胃癌患者的胃液CEA及Ft水平均高于各对照组,P<0.01。54例胃癌患者联合测定了血清CEA、胃液CEA及胃液Ft,胃癌胃液中的CEA、Ft双项阳性28例,敏感性为51.85％、特异性为99.04％、阳性诊断价值为96.55％。由此提示,胃液CEA及Ft联合测定有助于胃癌的诊断。
CEA and Ft levels in serum and gastric juice were determined by radioimmunoassay in 58 patients with stomach cancer,43 patients with benign gastric disease,24 patients with esophageal cancer and 158 normal adults.The serum CEA level in gastric cancer patients was higher than that of normal adults (P<0.01) but no statistical differences were found between patients with stomach cancer and benign gastric disease nor esophageal cancer.The serum Ft level in gastric cancer patients was lower than those of all other groups (P<0.01 or P<0.05).The levels of CEA and Ft in gastric juice were obviously elevated in patients with stomach cancer.CEA in serum and CEA and Ft in gastric juice were determined in 54 of 58 patients with stomach cancer.The rates of sensitivity,specificity and positive predictive value were 51.85%,99.04% and 96.55% respectivly when both CEA and Ft in gastric juice were combined.Therefore,the combined determination of CEA and Ft in gastric juice is helpful in the diagnosis of stomach cancer.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1992年第3期183-186,共4页
Chinese Journal of Clinical Oncology
关键词
癌胚抗原
铁蛋白
胃肿瘤
诊断
CEA(carcinoembryonic antigen)
Ferritin(Ft)
Diagnosis
Stomach cancer
