摘要
本文报告1979年10月～1987年9月245例食管癌根治切除术。术后严重肺并发症发生率术前放疗组为9.4％(5/52),单纯手术组为1.5％(3/193) (P<0.01)。作者根据大体观察、肺活检及临床过程分析认为:在肺受潜在放射性损伤后,手术中机械性压迫和纵隔淋巴结清扫所致的肺淋巴阻滞,可诱发放射性肺炎。文中对本病的诊治及预防进行了探讨。
Out of a series of 254 cases of cancer of the esophagus,serious pulmonary complication occurred in 9.4%(5/52) of patients who had received radiotherapy before radical resection,and in 1.5%(3/193) of patients without radiotherapy prior to resection.There was significantly higher incidence of pulmonary complication in the former group (P<0.01). Macroscopic,microscopic as well as clinical observations revealed that on the basis of potential irradiation injury of the lung,the anatomical damage caused by surgical manipulation and the lymphatic stasis resulting from dissection of the mediastinal lymph nodes might be conducive to radiation pneumonia or even ARDS.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1992年第2期108-110,共3页
Chinese Journal of Clinical Oncology
关键词
食管肿瘤
放射疗法
手术
肺炎
Esophageal carcinoma
Combined radiosurgical approach
Radiation pneumoniatis
Postoperative complications
