摘要
选出鼻咽癌病例及正常人对照各32例。测定放疗前后外周血IL-2活性。结果表明:病例组放疗前IL-2活性显著低下,放疗后明显回升,但仍低于对照组(P<0.01)。4例肿瘤残存者IL-2活性回升不良。讨论认为:肿瘤负荷可能是抑制IL-2活性的主要因素,IL-2活性检测可能作为监测肿瘤负荷及估计肿瘤患者预后的指标。
IL-2 activity of peripheral blood was measured in 32 cases of nasopharyngeal car- cinoma and compared with 30 normal persons. Patients were assayed before and after radiotherapy. The results showed that preradiotherapeutic IL-2 activity was quite low and increased apparently after radiotherapy. IL-2 level was lower in 4 patients with residual tumor The results suggested that tumor load likely plays a major role in suppressing IL-2 activity and that IL-2 assay may probably be an index of moni- toring tumor load and predicting prognosis.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1992年第1期31-32,共2页
Chinese Journal of Clinical Oncology
关键词
白细胞介素-2
鼻咽肿瘤
癌
Interleukin 2(IL-2)
Activity
Nasopharyngeal carcinoma
