摘要
静注克班宁5mg/kg能使BaCl_2引起的大鼠心律失常迅速转为窦性节律;可明显提高乌头碱引起大鼠室颤和死亡的用量;能减少CaCl_2所致大鼠和氯仿所致小鼠的室颤发生率和死亡率;但不能提高豚鼠心脏哇巴因中毒的耐受量。
Crebanine (Cre) iv 5mg/kg could eonvert BaCl_2-induced arrhythmia into sinus rhythm in rats, and could significantly increase the tolerant dose of aconitine to produce ventrieular fibrillation(VF) and cardiac arrest (CA) in rata. The drug could also decrease the incidence of VF and CA by CaCl_2 in rats and by chloroform in mice, but had no proteetive effects on ouahain-indueed arrhythmias in guinea pigs.
出处
《中国中药杂志》
CAS
CSCD
北大核心
1992年第11期685-687,共3页
China Journal of Chinese Materia Medica
