摘要
目的 检测乳腺癌患者血清TPS和CA15 3水平及乳腺癌患者两疗程化疗前后两者水平的变化。为乳腺癌的临床诊断、病情监测提供新方法。方法 用ELISA法分别检测血清TPS和CA15 3水平。结果 乳腺癌患者血清TPS和CA15 3水平均较良性肿瘤患者高 ,差异有显著性。血清TPS和CA15 3诊断乳腺癌的敏感度和特异度无差别。乳腺癌患者两疗程化疗后血清TPS和CA15 3水平显著下降。结论 血清TPS和CA15 3均可作为乳腺癌诊断、病情监测的临床指标 。
Objective We measure the serum levels of TPS and CA153 in patients with breast neoplasm and the variation of them before and after chemotherapy in patients treated as breast cancer, in order to determine their clinical,significance in diagnosis and monitoring of breast cancer. Methods Serum levels of TPS and CA153 were both detected by means of ELISA. Results Both serum TPS and CA153 levels in carcinoma patients were significantly higher than that in benign patients. Serum TPS and CA153 showed similar sensitivities and specificities in diagnosis of breast cancer and their levels both decreased significantly after 2 course of chemotherapy. Conclusions Serum TPS and CA153 are both useful in the diagnosis and monitoring of breast cancer. Their clinical value can be increased by combined use of them.
出处
《齐齐哈尔医学院学报》
2004年第2期127-128,共2页
Journal of Qiqihar Medical University
基金
江苏省科技厅课题文章
课题号为BK2 0 0 1 1 66
中国自然科学基金资助
