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鼻息肉中炎症细胞及细胞因子研究现状 被引量：2

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摘要 鼻息肉是鼻科常见疾病之一,其发病机制尚不明确。鼻息肉中存在多种炎症细胞及调节因子,它们在鼻息肉病变的发生发展中起重要作用。本文重点对嗜酸性粒细胞、嗜中性粒细胞、肥大细胞、淋巴细胞和浆细胞及其相关细胞因子在鼻息肉中的表达及作用研究现状进行综述。
作者 陈红 刘红刚
机构地区 首都医科大学 首都医科大学附属北京同仁医院病理科
出处 《国外医学（耳鼻咽喉科学分册）》 2004年第2期92-95,共4页 Foreign Medical Sciences(Section of Otolray Ngology Foreign Medical)
关键词 鼻息肉 炎症细胞 细胞因子 研究现状
分类号 R765 [医药卫生—耳鼻咽喉科]
  • 相关文献

参考文献23

  • 1Hirschberg A, Jokuti A, Darvas Z, et al. The pathogenesis of nasal polyposis by immunoglobulin E and interleukin-5 is completed by transforming growth factor-beta1. Laryngoscope. 2003; 113:120-124.
  • 2Xu Rui,Li Y, Xie M,et al. Concentration, distribution and expression of interleukin-5 in human nasal polyp tissues. Chin Med J. 2002; 115:1386-1389.
  • 3Hogan MB, Piktel D, Landreth KS. IL-5 production by bone marrow stromal cells: implications for eosinophilia associated with asthma. J Allergy Clin Immumol. 2000; 106: 329-336.
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同被引文献20

  • 1徐春英,郑明秀,王东海.鼻息肉与细胞因子的相关性研究[J].国外医学（耳鼻咽喉科学分册）,2005,29(2):78-81. 被引量：9
  • 2王鸿,张罗,周兵,张伟,刘华超,刘铭,黄谦.慢性鼻窦炎鼻息肉与变应性因素相关性的探讨[J].中华耳鼻咽喉头颈外科杂志,2005,40(3):168-171. 被引量：80
  • 3乐建新,陈建军,孔维佳,檀惠芳,舒宏,施秋梅.鼻息肉组织中IL-4 IL-5 IL-6和IL-8的含量及其表达[J].临床耳鼻咽喉科杂志,2006,20(11):484-486. 被引量：9
  • 4BURGEL P R,CARDELL L O,UEKI I F,et al. Intranasal steroids decrease eosinophils but not mucin expression in nasal polyps [ J ]. Eur Respir J, 2004,24(4) :594-600.
  • 5SANCHEZ-SEGURA A, BRIEVA J A, RODRIGUEZ C. T Iymphocytes that infiltrate nasal poIyps have a specialized phenotype and produce a mixed TH1/TH2 pattem of cytokines [ J]. J Allergy Cjin Immunol, 1998,102(6) :953-960.
  • 6ZHANG N, HOLTAPPELS G, CLAEYS C, et al. Pattern of inflammation and impact of Staphylococcus aureus enterotoxins in nasal poIyps from southern China[ J]. Am J Rhinol, 2006,20(4) :445-450.
  • 7YOSHIFUKU K, MATSUNE S, OHORI J,et al. IL-4 and TNF-alpha increased the secretion of eotaxin from cultured fibroblasts of nasal polyps with eosinophil infiltration [ J ]. Rhinology, 2007,45 (3) : 235-241.
  • 8JACQUOT J, HAYEM A, GALABERT C. Functions of proteins and lipid in airway secretions [ J ]. Eur Respir J, 1992,5 (3) :343-358.
  • 9MEYER J E, BARTELS T, GOROGH T, et aI. The role of RANTES in nasal poIyposis[ J ]. Am J Rhinol, 2005,19 ( 1 ) : 15-20.
  • 10BACHERT C, WAGENMANN M, HAUSER U, et al. IL-5 synthesis is upregulated in human nasal polyp tissue[ J]. J Allergy CIin Immunol, 1997,99 ( 6 ) : 837-842.

引证文献2

二级引证文献3

国外医学（耳鼻咽喉科学分册）
2004年 第2期

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