摘要
采用抗人μ重链单抗结合 APAAP 酶标记法对6～11周人早期胚肝的研究结果表明:6～6.5周的胚肝中未发现有μ^+细胞;1例47天的胚肝中最早观察到胞浆μ^+的前 B 细胞,7～11周的所有样本中都存在有前 B 细胞,因此胚肝中最早出现前 B 细胞的时期是在7周(49天)前后,最早出现的前 B 细胞为椭圆形大淋巴样细胞;在6～11周的胚肝中前 B 细胞呈散在分布,可能都是独立发生且处于分裂不活跃的状态。
The development of pre-B cells in human early fetal liver(6-11wks)was studied by using anti-McAb,combined with APAAP method.The results showed that pre-B cells,including two subpopulations(round and elliptic),appeared first in one of 6.7 wks fetal liver and then in all specimens from week 7 to 11.The differentiated stage of elliptic pre-B cells was possibly arlier than the round ones.The amount of μ^+ cells arised continuly during the 7th to 11th week.Those cells were scattered singly over the liver,and no pre-B cells proliferation was observes.
出处
《中国免疫学杂志》
CAS
CSCD
北大核心
1992年第2期77-81,共5页
Chinese Journal of Immunology
