摘要
目的:探讨常通口服液对术后肠粘连的防治作用机理。方法:采用损伤盲肠浆膜,结扎相应腹壁制成肠粘连模型,观察常通 口服液对粘连模型大鼠肠壁转化生长因子(TGF-β1)的影响,结果:常通口服液能抑制创面TGF-β1的过度表达。结论:常通口服 液通过抑制模型肠壁创面TGF—β1的过度表达而起到预防肠粘连的作用可能是其机理之一。
OBJECTIVE: To observe the preventive mechanism of Changtong oral liquid on postoperative intestinal adhesion .METHODS: The intestinal adhesion model was established by traumatizing cecal scrosa and ligating adjacent abdominal wall/The effect of Changlong oral liquid on the expression of TGF-β1 was examined by immunohistochemical method.RESULTS & CONCLUSION:Changtong oral liquid can decrease the expression of TGF - β1 of rats with adhesion .Maybe it is one of the mechanism that Changtong oral liquid can prevent postoperative intestinal adhesion.
出处
《中国药房》
CAS
CSCD
2004年第4期206-207,共2页
China Pharmacy
基金
国家新药基金资助项目(96-901-05-245)
关键词
常通口服液
术后肠粘连
转化生长因子
Changtong oral liquid
postoperative intestinal adhesion
TGF - β1
