摘要
目的 :探讨肝癌患者血清中血管内皮生长因子 (VEGF)的含量及临床意义。方法 :采用酶联免疫吸附法 (ELISA)对 1 2 2例肝癌患者及 1 1例经介入治疗的肝癌患者进行血清中VEGF的含量测定 ,并与 35例正常对照组进行比较。结果 :肝癌患者血清中VEGF含量明显高于正常对照组 ,P <0 0 1 ;1 1例肝癌患者经介入治疗 1个月内血清中VEGF含量明显下降 :前后比较差异有极显著意义 ,P <0 0 1。结论 :动态检测肝癌患者血清中VEGF水平 。
Objective To discuass the content of vascular endothelial growth factors (VEGF) in the hepatocellular carcinoma and its clinical significance.Methods By using the enzgme linked immunosorbent assay(ELISA) method VEGF contents in the serum of 122 liver carcinoma patients and 11 patients who received transcatheter closure were measured,and compared with that of 35 healthy people.Results VEGF content levers of liver carcinoma patients were higher than that of the control group, P <0 01.In 11 liver carcinoma patients after transcatheler closure the VEGF content dropped obviously, P <0 01.Conclusion Dygnamic VEGF levers can be used as important references in the therapeutic effect and prognosis.
出处
《肿瘤防治杂志》
2003年第7期716-717,共2页
China Journal of Cancer Prevention and Treatment
关键词
肝肿瘤/病理学
内皮生长因子
酶联免疫吸附测定
liver neoplasms/pathology
endothelial growth factors
enzyme linked immunosorbent assay
