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大环内酯类抗生素研究进展

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摘要 大环内酯类抗生素(macrolides)是一类化学结构和抗菌作用相近的抗菌药物.按其大环结构含碳母核的不同,分为14、15和16元环大环内酯类抗生素[1].50年代14元环的红霉素因对革兰阳性菌抗菌作用强,对治疗院外获得性呼吸道感染,皮肤软组织感染等具有良好疗效,而广泛用于临床.
出处 《黑龙江医药》 CAS 2004年第2期133-135,共3页 Heilongjiang Medicine journal
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  • 1赵香兰.大环内酯类抗生素研究进展[J].中国临床药理学杂志,1992,8(4):232-239. 被引量:14
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  • 8Koui O,Kanda T,Ohm ya K .et al. Purification and Characterization of Macrolide 2'.Phosphotransferase from a Strain of Eschericahia coli That ls Highly Resistant to Erythromycin[J].Antimicrob Ag Chenother.1989,33(8):1354.
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