摘要
分别在Pd/C、FeOOH和FeCl3·6H2O/C三种不同催化剂存在下,由水合肼还原2,2 二(4 羟基 3 硝基)苯基丙烷(1)合成了2,2 二(3 氨基 4 羟基)苯基丙烷,筛选出成本低、收率高的理想催化剂为FeCl3·6H2O/C。当物料配比n(水合肼):n(1)=5:1,反应起始温度为70℃,反应时间为80min时,收率为93 0%。产物经重结晶纯化后,由元素分析、红外光谱、核磁共振谱和质谱对其结构进行了表征,确证了产物的结构。
2,2-Bis(3-amido-4-hydroxyphenyl)-propane was synthesized by catalytic reduction of 2,2-Bis(4-hydroxy-3-nitrophenyl)-propane(1) with hydrazine hydrate in the presence of Pd/C,FeOOH and FeCl_3.6H_2O/C respectively. The results showed that the ideal catalyst was FeCl_3.6H_2O/C which gave high yield and had low cost. The yield was 93% when n (hydrazine hydrate):n(1)=5:1,temperature 70?℃, and reaction time 80?min. The structure of the product, which was crystallized, was certified by elementary analysis, IR,~1HNMR,^(13)CNMR and MS.
出处
《精细化工中间体》
CAS
2004年第1期18-20,共3页
Fine Chemical Intermediates
基金
:中南林学院青年科研基金 (项目编号 0 480 )
