摘要
目的 探讨脑神经胶质瘤的临床特征及其诊断和治疗方法。方法 回顾性分析9例经开颅手术或定向活检证实为脑神经胶质瘤的临床表现、影像学资料及治疗效果。结果 9例均有颅高压表现,CT扫描共发现23个病灶,其中病灶累及3个脑叶者5例,累及2个脑叶者4例。CT平扫病灶呈高密度5个,等密度5例,低密度13例,大多数病灶强化不明显,瘤周轻中度水肿。4例行MRI检查,发现胼胝体肥大2例。9例均获得半年以上随访。结论 脑神经胶质瘤CT扫描易误诊为转移瘤,MRI扫描对脑神经胶质瘤诊断有一定的价值,确诊依赖于病理检查。手术切除程度是决定预后的重要因素,术后分割放疗是控制肿瘤生长及延迟复发的重要辅助治疗手段。
Objective To investigate the clinical features, diagnosis and treatment of neurogliomatosis cerebri.Methods The clinical manifestation, imaging information and therapertric results of 9 patients with neurogliomatosis cerebri confirmed by pathological examination after operation or oriented biopsy were analyzed retrospectively. Results All 9 cases had symptoms of intracranial hypertension, and 23 foci were showed by CT scanning,5 foci with high density ,5 foci with equal density and 13 foci with low density. No enhancement was demonstrated in 8 foci,and slight or moderate enhancement in 15 foci. All foci had paratumoral edema in different degrees.The foci involved 3 lobes in 5 cases, and 2 lobes in 4.2/4 cases showed hytertrophy of corpus callosum by MRI examination. All 9 cases were followed up for more than half a year. Conclusions Neurogliomatosis cerebri is prone to be mis-diagnosed as metastatic tumor and MRI scanning is valuable to the diagnosis. Confirmed diagnosis depends on pathological examinantion. The degree of operational incision is an important factor affecting prognosis and post-operational radiotherapy is an important accessory treatment method to inhibit growth of tumor and postpone the recurrence of tumor.
出处
《中国肿瘤临床与康复》
2004年第1期69-71,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
