摘要
目的 寻找复方岗梅冲剂最佳提取工艺。方法 采取正交试验 ,以水的用量 ,提取时间和提取次数 3个因素 ,每个因素选取 3个水平进行实验 ,以测定抑菌作用和浸膏得率作为考察指标。结果 因素C对抑菌作用有非常显著性 (P <0 .0 1) ,因素C对浸膏得率和因素B对抑菌作用有显著性 (P <0 .0 5和P <0 .1) ,因素B对浸膏得率和因素A对浸膏得率、抑菌作用无显著性 (P >0 .1)。结论 最佳工艺A1B1C1,即用 11倍水提取 3次 ,每次 1.5h .。
OBJECTIVE To find the best extracting procedure of Gangmei compound granules. METHOD An orthogonal test was used. The solvent dosage(A), extracting time(B) and extracting times(C) were the three factors in the experiment and three levels of each factor were chosen . The bacteriostatic effect of the extract and the yield of extracte were studied.RESULTS The factor C had very significant effect on the bacteriostatic tests both Staphylococus aureus and β-hemolytic Streptococcus (P<0.01). The factor C had significant on the test of extraction (P<0.05)and the factor B had significant effect on the bacteriostatic tests (P<0.05 and P<0.1). The factor B had no significant effect on the test of extraction and the factor A had no sighificant difference effect on the test of extraction and the bacteriostatic tests (P>0.1). CONCLUSION The best extracting procedure is A 1B 1 C 1, which means extracting 3 times by using 11 times of water, 1.5 h each time.
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2004年第1期29-30,共2页
Chinese Journal of Modern Applied Pharmacy
基金
湛江市科技重点攻关项目 47号 ( 99 2 0 0 1)
关键词
复方岗梅冲剂
正交试验
提取工艺
Gangmei compound granules
orthogonal test
the extracting procedure
