摘要
目的:探讨旋转的恒定磁场对神经内分泌活动的影响及与止痛的关系,从而探索磁场止痛的机制。方法:用WD-6000多功能治疗仪(恒定磁场强度为0.6T,转速为240r/min)对10只新西兰兔和30例运动系统疾病或癌症疼痛患者进行磁场处理,9例患者(对照组)接受假磁场处理。分别在处理前后抽取血样,用放射免疫方法测定其血浆中β-内啡肽含量。结果:磁场处理后新西兰兔血浆β-内啡肽浓度为(83.7±9.8)pmol/L,显著高于处理前犤(38.3±15.2)pmol/L犦(t=8.69,P<0.01);实验组分别为(8.7±3.0),(58.2±21.6)pmol/L(t=12.48,P<0.01)。对照组的血浆β-内啡肽浓度在处理前后差异无显著性意义犤(8.7±0.5),(9.4±0.7)pmol/L犦(t=1.00,P>0.05)。结论:磁场能促使机体血浆β-内啡肽显著升高。此种变化是构成磁场止痛的内在基础之一。
AIM:To investigate the relationship between the influence of rotating and stationary magnetic field on neuroendocrine and its analgesic effect so as to explore the analgesic mechanism of magnetic field. METHODS:New Zealand rabbits and voluntary patients with pain were treated with magnetic field,using the HMF 6 000 multifunctional therapeutic equipment(magnetic field intensity of 0.6 T and rotational speed of 240 r/min).Blood samples were collected before and after the treatment to measure the contents of plasma β endorphin with radioimmunoassy. RESULTS: The mean plasma β endorphin concentration of rabbits after the magnetic field treatment was (83.7±9.8) pmol/L,significantly higher than that before the magnetic field treatment[(38.3±15.2)pmol/L](t=8.69,P< 0.01). The mean plasma β endorphin concentration of the patients with pain after the magnetic field treatment was (58.2±21.6) pmol/L,significantly higher than that before the magnetic field management[(8.7±3.0) pmo/L](t=12.48, P< 0.01).However,the concentration of plasma β endorphin patients in the control group was not significantly different after fake magnetic field management[(8.7±0.5)pmol/L vs (9.4±0.7) pmo/L](t=1.00,P >0.05). CONCLUSION:Magnetic field management increases the blood concentration of plasma β endorphin,which may be the internal basis of analgesic effect of magnetic field management.
出处
《中国临床康复》
CAS
CSCD
2004年第5期994-995,共2页
Chinese Journal of Clinical Rehabilitation
基金
国家自然科学基金(2001年50177018
2002年30270208)~~
