摘要
分别用 4 %的 EX- 313与 0 .5 %的戊二醛处理牛颈静脉带瓣胶原管道 ,所获的材料分别进行外观、扫描电镜与光镜检查 ;另外进行大鼠皮下埋植试验 ,生物力学的测试 ,所获的数据进行 t检验。EX- 313处理后的材料比戊二醛处理者质地更接近天然血管 ,结构间充满空隙 ,抗张强度与戊二醛处理者相当 ,抗钙化方面 EX- 313处理者明显优于戊二醛处理者。用亲水性交联剂 EX- 313处理的生物材料在抗钙化与顺应性方面比戊二醛更有优势 。
The bovine jugular veins were divided into two groups and treated with 4% EX-313 and 0.5% glutaraldehyde respectively, and then they were examined with naked-eye, microscope and scanning electron microscope. Biomechnics test and dorsal implantation in rats were performed. The aquired data were processed and subjected to t-test. The EX-313 fixed material was more pliable than the glutaraldehyde treated material, and the former had higher anticalcification than the latter. In conclusion, the hydrophilia crosslinking agent EX-313 is superior to glutaraldehyde in treating biomaterials, and the bovine jugular vein tanned with EX-313 should be a promising material for repairing in cardiovascular surgery.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
2004年第1期66-68,71,共4页
Journal of Biomedical Engineering
基金
国家自然科学基金资助项目 ( 3 9870 2 0 7)
关键词
亲水性交联剂
牛
颈静脉
生物材料
Crosslinking Bovine jugular Anticalcification Congenital heart disease
