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星形细胞在神经再生中的作用 被引量:1

The Role of Astrocytes in Neurogenesis
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摘要 神经干细胞和骨髓间质细胞具有增殖及分化为神经元的潜能,作为替代细胞为脑损伤后的神经再生带来了希望。最近的研究发现,成年颗粒下层和脑室下带等脑区的星形细胞具有干细胞的特性,在一定条件下可分化为神经元,并能提高神经的可塑性。探讨星形细胞对神经再生的影响,有助于重新认识星形细胞的功能及其在神经再生中的作用。 Neural stem cells and bone marrow stromal cells have the potential to proliferate and differentiate into neurons. As a kind of cell replacement, stem cells are promising in neurogen-esis after cerebral injury. Recent investigations have found that astrocytes from adult subventricu-lar zone (SVZ) and subgranular layer (SGL) had the characteristics of stem cells, and could differentiate into neurons and improve the neural plasticity under certain conditions. The exploration a-bout effects of astrocytes on neurogenesis may help to reconsider the function of astrocytes and their effect on neurogenesis.
作者 董丽萍 袁芳
出处 《国外医学(脑血管疾病分册)》 2004年第1期71-73,共3页 Foreign Medical Sciences Cerebrovascular Diseases
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