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神经源性疼痛动物模型的差异比较 被引量:3

Differences of neuropathic pain in animal models
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摘要 神经源性疼痛是由于外周或中枢神经损伤引起的持续性疼痛。临床前研究常用的动物模型大致可分为3类:不同的作用方式造成的外周神经损伤模型,化疗药物或鞘内注射强啡肽造成的化学损伤模型及糖尿病性神经痛模型。尽管这些神经源性疼痛动物模型在一定程度上模拟了临床上的疼痛症状,但它们在发病时程,持续时间,病理机制及对药物反应性方面等存在着差异。
出处 《中国临床康复》 CSCD 2003年第31期4272-4273,共2页 Chinese Journal of Clinical Rehabilitation
基金 国家自然科学基金(20302015)
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