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核因子κB受体活化剂研究进展 被引量：2

receptor activator of nuclear factor -κB
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摘要 核因子κB受体活化剂 ,是肿瘤坏死因子受体超家族成员 ,是骨保护素配体在破骨细胞上的受体 ,骨保护素配体通过与核因子κB受体活化剂结合 ,将细胞分化等信号传入破骨细胞前体内 ,促进其分化、融合 ,并促进成熟破骨细胞的激活过程。 Receptor activator of nuclear factor-κB, a transmembrane member of the tumor necrosis factor receptor superfamily, is the receptor of osteoprotegerin ligand on the membrane surface of osteoclasts. Osteoprotegerin ligand exerts its biologic effects such as stimulating osteoclasts differentiation, fusion and activating the mature ones through binding to receptor activator of nuclear factor-κB. [
作者 白玉娣 杨富生
机构地区 第四军医大学口腔医学院
出处 《牙体牙髓牙周病学杂志》 CAS 2003年第7期415-417,共3页 Chinese Journal of Conservative Dentistry
关键词 骨保护素配体 核因子κB受体活化剂 破骨细胞 osteoprotegrin ligand receptor activator of nuclear factor-κB osteoclast
分类号 R780.2 [医药卫生—口腔医学]
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参考文献18

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同被引文献14

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  • 3Simonet WS,Lacey DL,Dunstan CR,et al.Osteoprotegerin: a novel secreted protein involved in the regulation of bone density[J].Cell,1997,89(2):309-319
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  • 6Suda T. How is bone formed and resorbed ?- molecular mechanisms of bone formation and resorption[J].Rinsho Byori,2002,50(3):267-72
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牙体牙髓牙周病学杂志
2003年 第7期

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