摘要
为了研究脉压指数与颈动脉内膜中层厚度的关系 ,对 334例老年人行颈动脉内膜中层厚度超声检测并进行测压 ,分别以脉压≤ 6 0mmHg、6 1～ 80mmHg、81～ 10 0mmHg及 >10 0mmHg和脉压指数≤ 0 .4 0 0、0 .4 0 1～ 0 .5 0 0、0 .5 0 1～ 0 .6 0 0及 >0 .6 0 0分为四个亚组进行分析。结果发现 ,随着脉压和脉压指数的增加 ,颈动脉内膜中层厚度和收缩压均随之增加 ,脉压指数组舒张压进行性下降 ;Spearman’s相关分析发现 ,颈动脉内膜中层厚度与脉压指数相关性最佳 ;多元逐步回归分析显示 ,颈动脉内膜中层厚度仅与脉压指数、年龄具有显著回归效果 ,脉压指数的标准回归系数远大于年龄。结果提示 。
Aim To investigate the relationship between pulse pressure index (PPI) and carotid intima media thickness (IMT). Methods A total of 334 elderly patients were divided into 4 subgroups according to the level of pulse pressure (≤60 mmHg, 61～80 mmHg, 81～100 mmHg, >100 mmHg) and PPI (≤0.400, 0.401～0.500, 0.501～0.600, >0.600) respectively. Parameters of blood pressure, clinical features and carotid IMT were analyzed. Results The carotid IMT, systolic blood pressure, and age all increased when pulse pressure and PPI increased. However, diastolic blood pressure decreased with PPI increasing, but not when pulse pressure increased. The carotid IMT correlated best with PPI in Spearman's correlation analysis. The multiple factor stepwise regression analysis showed that only the regression of carotid IMT with PPI and age were of great significance, and the standard regression coefficiency of PPI was higher than age. Conclusion The PPI is better than pulse pressure in evaluating sclerosis of vessels in elderly patients.
出处
《中国动脉硬化杂志》
CAS
CSCD
2003年第3期250-253,共4页
Chinese Journal of Arteriosclerosis
