摘要
目的 研究脉压与心肌肥厚及心电图异常的关系。方法 抽样调查 60岁以上人群12 4 3人并进行测压和心电图检查 ,对其中 73 9例高血压病患者进行分析。按平均压 <113mmHg(1mmHg =0 13 3kPa)、≥ 113mmHg分为二组 ,再以脉压≤ 60mmHg、61～ 80mmHg、81～ 10 0mmHg、>10 0mmHg分为四个亚组。结果 (1)随着脉压增加 ,心肌肥厚 ,心电图异常均逐渐增加 ,P <0 0 1。(2 )血糖、总胆固醇、甘油三酯、高密度脂蛋白 胆固醇、低密度脂蛋白 胆固醇、体重指数并不随脉压增加而改变 ,P >0 0 5。 (3 )脉压相同而平均压分别为 <113mmHg、≥ 113mmHg两组进行比较 ,心肌肥厚 ,心电图异常均无差异 ,而平均压≥ 113mmHg组的收缩压、舒张压、平均压均高于平均压 <113mmHg组 ,两者差异有显著性 ,P <0 0 1。结论 高血压病患者脉压比收缩压、舒张压与心电图的相关性更为密切。
Objective To investigate the relationships between pulse pressure (PP), myocardial hypertrophy and electrocardiographical abnormality (ECG). Methods A sampling survey on blood pressure and electrocardiographic examination among 1 243 subjects aged over 60 years was performed, and among them 739 essential hypertensive patients were analyzed. They were first divided into two groups according to mean blood pressure (MBP)<113 mm Hg or ≥113 mm Hg (1 mm Hg=0.133 kPa), then were divided into four pulse pressure (PP) subgroups (≤60,61 80,81 100 and >100 mm Hg). Results (1) The prevalence of myocardial hypertrophy, ECG abnormality, systolic blood pressure (SBP) and mean blood pressure (MBP) increased with increasing PP, but DBP decreased ( P< 0.01). (2) The levels of blood glucose, total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HCL C), low density lipoprotein cholesterol (LDL C) and body mass index (BMI) had no correlation with PP ( P> 0.05). (3) In patients with the same PP, no difference in the prevalence of myocardial hypertrophy and ECG abnormality was found between MBP<113 mm Hg and MBP≥ 113 mm Hg, but the SBP and DBP were significantly higher in the latter ( P< 0.01). Conclusion High PP in essential hypertensive patients is an independent risk factor in cardiac events. The significance of PP is higher than that of SBP and DBP in predicting cardiac events.
出处
《中华心血管病杂志》
CAS
CSCD
北大核心
2000年第1期50-52,共3页
Chinese Journal of Cardiology
关键词
高血压
脉压
心肌肥厚
心电图
Essential hypertension
Pulse pressure
Myocardial hypertrophy
Electrocardiogram
