摘要
目的 探讨事件相关电位 (ERPs)和视觉诱发电位 (VEP)在帕金森病中 (PD)的诊断作用。方法 对 6 0例正常对照组和 5 8例无认知障碍的 PD患者组进行了 ERPs和 VEP检测。结果 PD组 ERPs的 P30 0 波潜伏期较对照组的明显延长 (P<0 .0 5 ) ,波幅则较对照组明显降低 (P<0 .0 5 ) ;PD组 VEP的 P1 0 0 波潜伏期较对照组明显延长 (P<0 .0 5 ) ,而波幅则无显著性差异 (P>0 .0 5 )。结论 ERPs的 P30 0 和
Objective To investigate the changes of event-related potentials(ERPs)and visual evoked potentials in patients with Parkinson disease(PD).Methods ERPs and VEP were studied in 58 patients with PD(PD group)and 60 controlers(control group).Results The latency and amplitude of P 300 in PD significantly prolonged and reduced,both P<0.05,compared with the control group.The latency of P 100(VEP)was prolonged significantly but the amplitude was not reduced significantly,compared with the control group.Conclusion P 300 has specific value in detecting the subclinical cognitive impairment and P 100 is able to detect the function of visual conduction pathway.
出处
《山东医药》
CAS
北大核心
2004年第1期6-8,共3页
Shandong Medical Journal
关键词
事件相关电位
视觉诱发电位
诊断
帕金森病
认知功能障碍
Parkinson Disease Cognitive Impairment Event-related Potentials Visual Evoked Potentials
