摘要
目的:探讨活体肝移植中供体的评估及随访策略。方法:对30例活体供肝者的临床资料进行回顾分析。结果:供体的总剔除率为28.6%(12/42),病毒性肝炎是最重要的剔除原因(6/12)。供肝重量与受体体重之比(graft鄄recipientweightratio,GRWR)均数为(1.39±0.45)%。所有供体均顺利康复。供体肝功能一般在5～7d内均恢复正常。供体随访时间为1个月～8年,随访时间超过6个月者23例,康复时间为(6±1.5)个月。供肝者残留肝恢复正常体积的时间为6～14个月。术后(8±1.0)个月,86.7%(26/30)的供体恢复术前工作或劳动;30%(9/30)的供体出现过一过性症状,如腹部不适、疼痛等,其中22.2%(2/9)的供体主诉疼痛较严重,需要就医。随访显示,供体均因献肝而赢得社会、朋友的尊重。结论:活体肝移植不仅安全可行,且献肝可能对供、受体的感情、心理、家庭及社交产生良好的、积极的影响。
Objective: To study the evaluation and following-up strategy on living donors in Liver Transplantation (LDLT). Methods: A respective analysis was made on total 30 cases of living donors. Results: The elimination rate of living donors was 28.6%(12/42), and viral hepatitis was the most important factor in eliminating candidates(6/12). Graft-recipient weight ratio (GRWR) was (1.39±0.45)%. All the donors recovered uneventfully after operation, their liver function returned to normal on the 5th to 7th day. The following-up period ranged from 1m～8yrs, exceeding 6mos. in 23 donors. It took 6～14mos. for the residual liver to regenerate to its original size. Twenty-six of the donors (86.7%) returned to their normal work (8±1.0)mos. after operation. Some transitory symptoms, such as discomfort of belly, were found in 30% (9/30) of the donors, of whom 22.2%(2/9) had to be hospitalized for sometime. All the donors won respects from society and friends. Conclusions LDLT is a safe and feasible procedure. It helps to improve the emotional relationship, between donor and recipient, and to gain sympathy from the society.
出处
《外科理论与实践》
2003年第6期445-447,450,共4页
Journal of Surgery Concepts & Practice
基金
江苏省重点课题BJ98025
关键词
活体肝移植
供体
随访
并发症
肝功能
Liver transplantation Living donor Evaluation Follow-up
