摘要
报道２３５名正常小儿血清锌、铜参考值（μｍｏｌ／Ｌ）：新生儿１３．３±１．９、１２．６±２．２，１～３个月龄时偏低，４月龄后增加，且恒定在１５．６±３．２、１７．４±３．４。铜／锌比值为１．１±０．２。疾病组１８０例患儿血清锌降低，以厌食、缺铁性贫血降低明显。血清铜增加，以恶性血液病增加显著，且与病情相关。Ｇ６ＰＤ缺陷溶血组血清锌减少比非溶血组减少明显．与Ｇ６ＰＤ活性、Ｇ６ＰＤ缺陷致溶血之间存在着一定的关系。了解血清钟、铜含量及其比值，对某些小儿疾病的诊断、治疗和预后均有一定的参考价值。
In this paper, the reference serum levels of zinc and copper in 235 healthy children were reported. Serum concentration of zinc was 13.3± 1. 9 μmol/L, in neonate, lower during 1￣3 months. increased after 4 months. and then stable (15.6±3. 2 μmol/L), Serum concentration of copper was 12. 6±2. 2 μmol/L. lower during 1￣3 months, increased after 4 months. and then stable (17.4± 3.4 μmol/L). The ratio of copper/zinc was 1.1±0. 2. In 180 cases with diseases, the serum concentration of zinc was decreased, which was more obvious in patients with anorexia and iron deficiendy. The serum concentration of copper was increased, which was more obvious in patients with malignait hemotolagic diseases, in G6PD deficiency children, the serum zinc concentration was decreased more obvious in hemolytic group than that in non-hemolytic group. It was suggested that zinc was corelated with the G6PD activity and the hemolysis of G6PD deficency. Therefore, it provides refereace value for the diagnosis. treatment and prognosis of some diseases to understand the serum concentration of zinc and copper and their ratio.
出处
《广东微量元素科学》
CAS
1995年第10期50-54,共5页
Trace Elements Science
