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去整合蛋白及其抗肿瘤作用研究进展 被引量：3

Advanced research on antitumor effects of snake venom disintegrins
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摘要 去整合蛋白是一类分子量较小 ,由 49～ 84个氨基酸组成 ,富含半胱氨酸的生物活性因子。去整合蛋白二硫桥形成的环中含有精氨酸 -甘氨酸 -天冬氨酸 ( RGD)结构 ,能够竞争性地与整合素结合 ,从而抑制整合素参与的生理活动。去整合蛋白能够抗血小板聚集和肿瘤细胞转移 。
作者 孙德军 谷红东 杨春伟 赵轶卓 常淑芳 颜伟群 侯立中
机构地区 吉林大学再生医学科学研究所生化研究室 吉林省人民医院血液科
出处 《吉林大学学报（医学版）》 CAS CSCD 北大核心 2003年第6期860-863,共4页 Journal of Jilin University：Medicine Edition
基金 国家自然科学基金资助课题 (39870 375 )
关键词 肽水解酶类 金属内肽酶类 抗血小板聚集抑制剂 去整合蛋白 抗肿瘤作用
分类号 R730.1 [医药卫生—肿瘤]
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参考文献24

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同被引文献29

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吉林大学学报（医学版）
2003年 第6期

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