摘要
肌体蛋白质在与青石棉的相互作用过程中,组织结构对称性降低,结构疏松;青石棉的硅已与蛋白质中的烷基、胺基交联成键,存在明显的Si—O—C(N),Si—R新的吸收谱带;青石棉残留的粉尘仅为以硅为主的物质。石棉小体(斑)内的纤维表面基团和组织内的某些蛋白反应形成新的表面介体。染尘肌体组织在加热过程中,蛋白质类结构对称性降低并逐渐氧化,末端基团如—CH_3,—CH_2振动减弱。C—C长链骨架的分解,并可分成200,400和600℃三个相变温区。Si—O,Si—O-Si吸收加强,新生成的表面介体的稳定性(Si—O—C,Si—C,Si—CH_3)基团介于二者之间。在500℃以上,肌体组织、表面介体和体内残留纤维已全部破坏。体内青石棉被生物作用溶解和生化反应结合后,其热稳定温度大为降低。
In the course of the interaction between organism protein and crocidolite, the protein symmetry decreases and the structure loosens. The silicon of crocidolite has bonded with alkyl, amidocyanogen of protein, and new absorption bands of Si-O-C(N) and Si-R have clearly appeared. The residual substances of crocidolite are mainly silicon. The surface radicals of asbestos fiber reacted with some albumen in tissue and formed new surface medial-matter. When injected organism tissues were heated, the protein structural symmetry was reduced, oxidated gradually, and the vibration weakened at the end radicel such as -CH3, -CH2. There are three phase change areas at 200, 400, 600degreesC , and C-C long chain framework decomposition. Si-O and Si-O-Si peaks intensified and there are between the above the stable new formed surface medial-matters such as Si-O-C, Si-C and Si-CH3. Over 500degreesC, the organism tissues, surface medial-matter and remained crocidolite fiber were totally destroyed. Dissolved and combined with biological acting in rat, the thermal stability temperature of crocidolite becomes quite lower.
出处
《光谱学与光谱分析》
SCIE
EI
CAS
CSCD
北大核心
2003年第6期1086-1089,共4页
Spectroscopy and Spectral Analysis
基金
国家自然科学基金(40072020
49602025)
"四川省杰出青年基金资助计划"项目资助
