摘要
目的总结原发性肝癌的综合治疗的疗效。方法对 4 2 0例原发性肝癌病人的临床资料、治疗手段及随访资料进行回顾性分析。结果 32 7例病人得到随访 ,随访率为 78% ;全组病人 1、3、5年生存率分别为 4 0 9%、19 1%、12 4 %。其中根治性手术组 (无血管侵犯 ) 1、3、5年生存率分别为 75 9%、4 7 3%、4 0 1% ;根治性手术组中 ,手术前后TACE(transarterialchemoembolization)、DDS(drugdeliverysystem)或冷冻治疗对术后生存率均无影响 ,而癌灶有无血管侵犯对术后生存有重要意义 ;姑息性切除的 1、3、5年生存率分别为 39 6 % ,2 2 1%和 17 5 % ,在姑息性切除中 ,术后TACE或DDS置泵化学药物治疗均可提高肝癌病人的存活率。结论应用合理有序的综合治疗和肝癌个体化治疗是进一步提高肝癌疗效的关键。
ObjectiveTo verify the effect of comprehensive therapy for primary liver cancer (PLC). MethodsThe clinical data of 420 cases admitted to our hospital from Jan. 1994 to Jun. 2000 was analyzed retrospectively. Patients received hepatectomy and transarterial chemoembolization (TACE), drug delivery system (DDS) on case-to-case basis.Results Three hundred and twenty-seven patients were followed-up from 3 days to 81 months. The overall 1-, 3-, 5-year survival rates were 40.9%、19.1%、12.4%, respectively. 75.9%,47.3%,40.1% for patients undergoing radical resection and 39.6%,22.1%,17.5% in patients with palliative resection. TACE or DDS implantation after palliative resection was effective to enhance the survival rate. Conclusion The rational and scientific combination of multiple modality is important to prolong survival time of the patients with PLC.
出处
《中华普通外科杂志》
CSCD
北大核心
2003年第12期709-711,共3页
Chinese Journal of General Surgery
