摘要
目的:探讨肝切除加化疗治疗原发性肝癌的疗效.方法:回顾性分析我院1996年1月～2003年12月收治的380例肝癌患者的临床资料,根据不同方法分成2组:手术切除组(A组)130例,手术切除加化疗组(B组)250例.结果:手术切除加化疗组1、3和5年的复发率分别为21.2%、35.1%和45.3%,其1、3和5年累积生存率分别为68.2%、50.1%和21.8%,明显高于单纯手术切除组.术后化疗次数是影响手术切除疗效的重要因素.结论:肝切除术后加区域性化疗可降低肝癌术后复发率,提高了患者的生存率.
Purpose： To explore the therapeutic effects of hepatectomy and chemotherapy of primary liver cancer （PLC）Methods：The clinical data of 380 PLC patients admitted from January.1996 to December,2003 were divided into two groups：130 cases underwent hepatectomy and chemotherapy（B group）.Results：The 1-,3-and 5-year recurrence rates in the hepatectomy and chemotherapy group were 21.2%,35.1% and 45.3%,The 1,3and 5-year overall survival rates in the hepatectomy and chemotherapy group were 68.2%, 50.1% and 21.8%,with were signifieantly higher than heatectomy group.The number of chemotherapy courses affccted the effect of hepatectomy.Conclusions：Hepatectomy and regional chemotherapy may decrease tumor recurrence rates and improve the disease-free survival rates in patients with PLC.
出处
《中国癌症杂志》
CAS
CSCD
2005年第4期365-368,共4页
China Oncology
