摘要
目的 :探讨食管小细胞癌的临床病理特点及组织发生和诊断。方法 :分析 4例食管小细胞癌的临床病理资料 ,对肿瘤进行光镜观察 ,并做免疫组化。结果 :根据细胞形态分为单纯小细胞型 2例、中间细胞型 1例、复合细胞型 1例。免疫组化染色 NSE、Syn、Cg A阳性率分别为 4 / 4、3/ 4、4 / 4。结论 :食管小细胞癌是一种高度恶性肿瘤 ,确诊主要依靠病理组织学检查 ,免疫组化的合理应用可提高诊断率 ,组织发生上支持来自全能干细胞。
Objective:To study the clinical pathological character,histogenesis and diagnosis of esophageal small cell carcinoma.Methods:The clinical pathological data of 4 patients were analyzed,and all cases were studied with light microscopy and immunohistochemistry.Results:According to the cancer cell type,these cases were classified into small cell type,middle cell type and mixed cell type.Immunohistochemically,4,3,4 cases showed positive for NSE,Syn,and CgA respectively.Conclusion:This study indicated that small cell carcinoma of esophagus was highly malignant.The confirmed diagnosis depends on the pathological biopsy.The application of immunohistochemical method may raise the diagnostic rate and this kind of tumor may originate from the multipotent stem cells.
出处
《肿瘤研究与临床》
CAS
2003年第6期377-379,共3页
Cancer Research and Clinic
关键词
食管
小细胞癌
病理学
Esophagus
Small Cell Carcinoma
Pathology
