摘要
目的 建立胎儿颈部软组织厚度 (nuchalskinfoldthickness ,NT)的正常参考值 ,以便为产前超声诊断胎儿染色体异常提供参照。方法 经腹超声测量 3 2 0 3例中晚孕期胎儿颈部软组织厚度 ,并进行统计分析。结果 初步得出各孕周胎儿NT的参考值范围。NT随着孕周增加而增长 ,其回归方程 :NT =-1.44 8+0 .40 1×孕周 (r =0 .790 ,P <0 .0 0 0 1)。结论 NT的变化遵循胎儿发育的规律 ,有其本身的固定图像特征。本文提出的各孕周的NT超声测值 ,对胎儿染色体异常的筛查有重要参考价值。其敏感性为 66.67% ,特异性为 95 .0 6% ,准确性为 95 %。
Objective To investigate normal measurements of nuchal skinfold thickness in healthy fetus as a reference for screening fetal chromosome abnormity in prenatal ultrasonography.Methods The measurements of NT in 3202 fetuses with gestational age from 12 to 40 weeks were statistically analyzed. Results A priliminary measurements of the fetal nuchal skinfold thickness in 12-40 weeks gestation were analyzed, which indicated that NT increased with gestation. Its regression equations was: NT=-1.448+0.401×week,(r=0.790,P<0.0001). Conclusion Increased thickness of the nuchal skin fold in healthy fetus followed gestational growth. The ultrasonographic measurements can provide an important reference in prenatal screening of fetal chromosome abnormality.
出处
《中国医学影像技术》
CSCD
2003年第12期1715-1717,共3页
Chinese Journal of Medical Imaging Technology
基金
广西科技厅科学研究与技术开发资助项目 (桂科攻 981 70 95)
