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基因变异与子宫内膜异位症的发生 被引量:1

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摘要 基因的变异在子宫内膜异位症(EMs)的发生和发展中有很重要的作用。研究发现EMs的发生有家族遗传倾向,一级亲属的患病率高于一般人群。某些卵巢癌的候选基因在EMs中也能检测到。孕激素受体(PR)的基因在异位内膜中有变异,无PR-B表达。氧化应激反应也可能诱发EMs发生,使用抗氧化剂能阻止诱发兔EMs。环境毒素二噁英(dioxin)可能会激活体内的某些化学酶系而诱发EMs。
作者 丁岩 温浩
出处 《国外医学(妇产科学分册)》 2003年第6期372-375,共4页 Foreign Medical Sciences(Obstet Gynecol Fascicle)
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