摘要
目的:对比性研究NP方案与NIP方案治疗非小细胞肺癌的临床疗效和毒副反应。方法:24例Ⅲ～Ⅳ期非小细胞肺癌采用NP方案:NVB 25mg/m2,iv,d1.8;DDP 80mg/m2,iv,d2。23例Ⅲ～Ⅳ期非小细胞肺癌采用NIP方案:NVB 25mg/m2,iv,d1.8;DDP 80mg/m2,iv,d2;IFO 1.2mg/m2,iv,d1-3。结果:NP方案组有效率45.8％,NIP方案有效率56.5％。毒副反应:剂量限制性毒性为骨髓抑制。结论:NIP方案治疗非小细胞肺癌有效率高,毒副作用能耐受。
Objective: To evaluate and compare the clinical effects and toxic reaction of NP regimen and NIP regimen for advanced Non-small cell lung cancer (NSCLC). Methods: Twenty-four III-IV phase Non-small cell lung cancer were treated with NP regimen: NVB 25mg/m2iv d1.8, DDP 80mg/m2iv d2. Twenty-three III-IV phase Non-small cell lung cancer were treated with NIP regimen; NVB 25mg/m2iv d1.8, DDP 80mg/m2iv d2, IFO 1. 2mg/m2iv d1-3. Results: The results showed that the response rates of NP group and NIP group were 45. 8% and 56. 5% respectively, toxic reaction: The dose limiting toxicity was neutropenia which was seen in all treated cases. Conclusion: NP regimen for treating advanced NSCLC has a high response rate and tolerable side effects.
出处
《临床肿瘤学杂志》
CAS
2003年第6期431-432,435,共3页
Chinese Clinical Oncology
