摘要
目的 :评价干燥脱水法长期保存角膜片在板层治疗性角膜移植术中的效果。方法 :保存角膜片选自我院眼库干燥保存符合临床标准、复水透明的完整角膜片 ,临床病例选自我院角膜病组 1976年 8月～1999年 12月期间行板层治疗性角膜移植患者 12 67例 ,从手术前后视力比较、原发病灶控制、植片存活情况进行临床效果综合分析。结果 :保存角膜片复水透明合格率为 94 9% ,临床治愈率 :感染性角膜溃疡 /穿孔 88 8% ,血管翳性全角膜白斑 98 3 % ,化学及热烧伤 (穿孔 ,睑球角粘连等 ) 92 1% ,圆锥角膜及急性圆锥角膜 99 5 % ,角膜变性 (边缘性及前基质层 ) 99 0 % ,其他88 9% ,平均总治愈率 93 5 %。结论 :1 对各种严重的角膜感染、药物治疗无法控制的病人 ,治疗性角膜移植术是唯一有效的方法。 2 采用无水氯化钙 -硅胶干燥脱水长期保存的供体角膜能为临床随时提供角膜材料 ,是一项简单易行、便于推广应用的成功率很高的保存方法。
Objective:To evaluate the effects of long-time dehydrated preservation of donor corneal grafts. Methods:1267 cases of therapeutic keratoplasty were performed with long-time dehydrated preservation of donor corneal grafts from Xian Eye Bank.The preoperative and postoperative visual acuities,controlling of original focus,revival scene of donor corneal grafts were analyzed. Results:The transparent rate of donor corneal grafts after re-hydration was 94.9%.The clinical effective rates in infective corneal ulcer/perforation,pannus totalis and corneal opacity,chemical burn and heat burn (perforation corneoblepharon),keratoconus and acute keratoconus,corneal degeneration(marginal,shallow of stroma) and other diseases were all over 88%,mean 93.5%. Conclusions:Long-time dehydrated corneal preservation in water-free calcium chloride-silica gel can provide clinical supply of corneal materials whenever necessary,it is an easy and simple,highly applicable method.
出处
《中国实用眼科杂志》
CSCD
北大核心
2003年第11期825-827,共3页
Chinese Journal of Practical Ophthalmology
