摘要
目的 观察穴位敷贴疗法对豚鼠血浆、支气管肺泡灌洗液中内皮素水平及血清、支气管肺泡灌洗液中 IL-2水平的影响。方法 采用卵蛋白致敏法制作豚鼠实验性过敏性哮喘模型 ,用穴位敷贴法治疗。结果 治疗组血浆、支气管肺泡灌洗液中内皮素水平明显低于致敏组 ( P<0 .0 1,P<0 .0 0 1) ,与正常组无明显差异 ( P>0 .0 5 ,P>0 .0 5 ) ;治疗组血清中 IL -2水平明显低于致敏组 ( P<0 .0 1) ,与正常组无明显差异 ( P>0 .0 5 )。结论 提示穴位敷贴可能通过降低血浆、支气管肺泡灌洗液中内皮素含量 ,降低血清中
Objective To observe the influence of point application therapy over the levels of endothelin (ET) in plasma and bronchoalveolar lavage fluid (BALF), and the levels of IL 2 in the serum and bronchoalveolar lavage fluid (BALF) of Guinea pigs. Methods Guinea pig model of experimental allergic asthma was created with ovalbumin sensitization, and point application therapy was applied to treat the Guinea pig models of experimental allergic asthma. Results The levels of ET in the plasma and bronchoalveolar lavage fluid (BALF) of the treatment group were significantly lower than the levels in the model group ( P <0.01, P <0.01), and they had no obvious difference from the levels of the control group ( P >0.05, P > 0.05 ), the IL 2 level in the serum of the treatment group was significantly lower that that of the model group ( P <0.01), and it had no obvious difference from that of the normal group. Conclusion It indicated that point application exerted its therapeutic effects on allergic asthma by lowering the ET contents in the plasma and bronchoalveolar lavage fluid as well as IL 2 content in the serum.
出处
《上海针灸杂志》
2003年第9期23-25,共3页
Shanghai Journal of Acupuncture and Moxibustion
基金
广东省高教厅资助项目 (96- 4 )
