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肺结核患者前炎症细胞因子作用的探讨 被引量:3

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摘要 目的 :探讨前炎症细胞因子在肺结核病理过程中的作用及临床意义。方法 :对 39例肺结核患者采用双抗体酶联免疫吸附法测定肿瘤坏死因子 α(TNFα)、白细胞介素 6 (IL- 6 )、白细胞介素 8(IL- 8)含量。结果 :肺结核组和正常对照组血清TNFα、IL- 6、IL- 8的水平相比 ,差异均有显著性 (P<0 .0 1 ) ,肺结核组中活动性肺结核组血清 TNFα、IL- 6、IL- 8水平显著高于非活动性肺结核组 (P<0 .0 1 )。结论 :作为前炎症细胞因子的 TNFα、IL- 6、IL- 8是肺结核患者在结核病理过程中的重要调节因子 ,其血清水平可作为监测病情活动的指标之一 ;对肺结核患者血清前炎细胞因子的深入研究可能为结核病的治疗开辟新途径。
作者 马秀玲
出处 《广西医学》 CAS 2003年第12期2431-2432,共2页 Guangxi Medical Journal
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同被引文献35

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