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结扎家兔肾血管的实验性研究 被引量:1

EXPERIMENTAL STUDIES ON THE RENAL VESSELS LIGATION IN RABBITS
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摘要 36只兔分对照组和实验组。实验组施行了左肾动脉或左肾动、静脉同时结扎手术。术后动物生活正常,3~8个月后杀死。分别观察肾侧支循环的建立及肾的大体解剖、显微结构和组织化学变化等。1.结扎左肾血管后,因未能建立有效的侧支循环,致使左肾萎缩。右肾均呈现明显的代偿性肥大,其重量也明显增加。2.代偿肥大肾是由于原有肾单位的代偿肥大,以及其间结缔组织增生所造成的。3.代偿肥大肾与对照组相比,在 JGI、PAS、AIP 等方面均无显著差异。这可能提示代偿肥大肾至少在肾素分泌和重吸收机能等方面基本正常。 36 rabbits were divided into control and experimental groups.In the experimen- tal group,the left renal artery was ligated or the left renal artery and vein were ligated simultaneously.All the animals were alive.After 3—8 months of the opera- tion,the rabbits were killed.The establishment of collateral circulation and the anatomical,histological and histochemical changes of the kidny were observed.The results obtained were as follows:1.Ligation of the left renal vessels causes atrophy of the left kidney on account of the failure of collateral circulation establishment.The right kidney of the experimental group showed obviously compensatory hypertrophy. The weight of the compensatory hypertrophied kidneys obviously increased.2.The compensatory hypertrophic growth of kidneys is due to the hypertrophy of existing n(?)phrons and the hyperplasia connective tissue.3.comparison of the controls,in the JGI,PAS and AlP reactions with the compensatory hypertrophied kidneys, there were no striking differences.The results suggest that the compensatory hyper- trophied kidneys were normal at least on the renin secretion and reabsorption func- tion.
出处 《解剖学报》 CAS CSCD 北大核心 1989年第2期121-124,共4页 Acta Anatomica Sinica
关键词 肾动脉 侧支循环 代偿肥大 Renal artery Collateral circulation Compensatory hypertrophy Juxtaglomerular cell granule Rabbit
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  • 1吴阶平,中华实验外科杂志,1985年,2期,1页
  • 2曾小鲁,动物学杂志,1982年,4期,48页
  • 3傅霍,江苏医药,1980年,11期,24页
  • 4韩振藩,中华外科杂志,1966年,14卷,39页

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