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重症肝炎合并感染208例临床分析 被引量:2

Clinical analysis of 208 hepatitis gravis patients complicated with other infections.
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摘要 目的 分析重型肝炎患者合并感染的状况。方法 对我院 1998~ 2 0 0 1年间收治的 2 0 8例重型肝炎患者发生感染的情况进行分析。结果  2 0 8例重型肝炎患者共发生合并感染 112例 ( 5 3.8% ) ,老年组 2 8例 ,合并感染率为73 7% ( 2 8/38) ,明显高于非老年组 ( 4 9.4% ,84/170 ) ,P <0 .0 1。感染发生部位以腹腔为主 ,其次是胆道、上呼吸道和肺部。 112例中 ,有 5 6例有前预防性使用广谱抗生素 ,14例接受过腹腔穿刺 ,所有患者血清胆红素均高于 117 1μmol/L ,发生感染的病死率为 71 4% ( 80 /112 ) ,未发生感染的病死率为 14 6 % ( 14 /96 )。差异有显著性意义 (P <0 .0 5 )。结论 重型肝炎感染的发生率很高 ,是导致死亡的重要因素 ,有效地控制感染是提高存活率的重要手段。 Objective To analyse the status of 208 severe hepatitis patients complicated with other infections.Methods The results of complicated infections of 208 severe hepatitis patients treated in this hospital were analysed according to different age groups.Results It was observed that out of the 208 severe hepatitis patients complicate infections occurred in 112 cases (53.8%) being 28 cases in the old age groups(73.7%)significantly higher than that in other age groups(49.4%,84/170,P<0.01).The main sites of infections were in the abdominal cavity,followed by bilary passage,upper respiratory tract,and lung.Out of the 112 cases with complicated infections 56 cases were previously tract,and lung.Out of the 112 cases with complicated infections 56 cases were previously given antibiotics of broad spectrum for preventive purpose and 14 were received abdominal puncture.high level of serum bilirubin(>117.1 umol/L)were observed in all the patients.The fatality rate in those with complicated infections were found to be higher (71.4%,80/112)than those without complicated infections(14.6%,14/96)and the differences were significant.(P<0.05).Conclusion It has been noticed that high incidence of complicated infections occurred to patients with severe hepatitis to have been an major factors leading to death.Thus to effectively control complicated infection is an important measure for enhancing survival rate.
作者 徐玉仙
出处 《中国热带医学》 CAS 2001年第4期329-330,共2页 China Tropical Medicine
关键词 重症肝炎 合并症 感染 血浆白蛋白 血清总胆红素 Severe hepatitis Complicated infections Clinical analysis.
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