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重型病毒性肝炎患者病原学及预后的研究 被引量:16

A STUDY OF ETIOLOGY AND PROGNOSTS ON PATIENTS WITH SEVERE VIRAL HEPATITIS
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摘要 对94例重型病毒性肝炎进行了病毒标志的研究,并分析了几种影响重型肝炎预后的因素。结果发现:单纯HBv感染42例(44.7%);混合感染共50例(53.2%),其中HBV与HCVl9例(20.2%).HBV与NDV13例(13.8%),HBV与HCV、HDVI0例(10.6%)HAV与KBV3例(3.2%),HAV与HBU、HCV3例(3.2%)HAV与HBv、HDVI例(1.1%).NAV与HBV、HCV、HDV1例(1.1%);病毒标志均阴性者2例(2.1%)。HBV、HCV和HDV混合感染者病情重,病死率高。血清总胆红素越高,凝血酶原活性越低,其病死率越高;有并发症者的预后差,而AMP升高者的预后较好;重肝的预后可能与年龄、性别无关。 erum Samples from 94 patients with severe viral hepatitis were tested for IgM anti-HAV,,HBV markers, anti-HCVand HDV markers. And the factors relating to prognosis were analysed. The results showed that 42(44.7%)cases werecaused by HBU infection alone,50(53.2%)cases were caused by various multiple infeetion and two(2.1%)cases were notidentified Among these cases.19(20.2%)cases were HBV and HCV coinfection,13(13.8%)cases were HBv and HDVcoinfection,10(10.6%)cases were multiple infection of HCU, and HDV,3(3.2%)cases were HAV and HBU coin-fection 3(3.2%)cases were multiple infection of HAV.HBV and HCV,one case(1.1%)was multiple infection of HAV、HBV and HDV ,one case(1.1%)was multiple infection of HAV 、HBU、HCV and HDV The patients caused by various mul-tiple infection of HBV、HCV and HDV were more critical and usually carried higher mortality. There were higher mortalityamonf patients with higher levels of total serum bilirubin and lower levels of prothrombin activity. The outcome of the pa-
出处 《肝脏病杂志》 CSCD 1994年第2期92-94,共3页
关键词 丁型肝炎病毒 重型 肝炎 病原学 预后 HBV HCV epatitis B Virus Hepatitis C Virus Hepatitis D Virus Hepatic failure
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